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特聘研究员、博士生导师
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联系方式
电话：15826063819
邮箱：libs@cqu.edu.cn；libaoshengqq@163.com
地址：重庆大学虎溪校区必赢线路检测中心711室
研究方向
1.有机合成方法学的发展
2.药物分子、活性化合物的合成及生物活性研究
3.小分子靶向药物的合成及其在肿瘤诊疗和转化医学等领域中的应用
代表性论文、专著和专利
以第一作者发表论文
1. Carbene-catalyzed reductive coupling of nitrobenzyl bromides and ketones via single-electron-transfer process. Bao-Sheng Li; Yuhuang, Wang; Rupert S. J. Proctor; Yuexia Zhang; Richard D. Webster; Song Yang; Baoan Song; Yonggui Robin Chi*, Nature Communications. 2016, 7, in press.
2. Carbene-catalyzed desymmetrization of 1,3-diols: access to optically enriched tertiary alkyl chlorides. Bao-Sheng Li; Yuhuang, Wang; Rupert S. J. Proctor; Zhichao, Jin; Yonggui Robin Chi*, Chem. Commun, 2016, 52, 8313.
3. Carbon–carbon bond activation of cyclobutenones enabled by the addition of chiral organocatalyst to ketone. Bao-Sheng, Li; Yuhuang Wang, Zhichao Jin, Pengcheng Zheng, Rakesh Ganguly & Yonggui Robin Chi*, Nature Communications. 2015, 6, 6207.
4. Cycloaddition of cyclobutenone and azomethine imine enabled by chiral isothiourea organic catalysts. Bao-Sheng Li, Yuhuang Wang, Zhichao Jin and Yonggui Robin Chi*, Chemical Science, 2015, 6, 6008.
5. Direct Synthesis of Spiro- and Fused-Hydrofurans via Tunable Tandem Semipinacol Rearrangement/Oxa-Michael Addition. Bao-Sheng, Li; Wen-Xing, Liu; Fu-Min, Zhang; Shao-hua, Wang; Yong-Qiang, Tu*; Xiao-Ping, Cao*,Chenistry - A European Journal, 2013, 19, 5246.
6. Copper(I)-catalyzed Intramolecular [2+2] Cycloaddition of 1,6-enyne-derived Ketenimine: an Efficient Construction of Strained and Bridged 7-substituted-3- Heterobicyclo [3.1.1] heptan-6-one. Bao-Sheng Li; Bin-Miao, Yang; Shao-Hua, Wang; Yong-Qiang, Zhang; Xiao-Ping, Cao*; Yong-Qiang, Tu*, Chemical. Science, 2012, 3, 1975. Highlighted by Synfacts, 2012, 8, 0868.
7.One-Pot Construction of Multi-Substituted Spiro-Cycloalkanediones by an Organocatalytic Asymmetric Epoxidation/Semipinacol Rearrangement. Bao-Sheng, Li; En, Zhang; Qing-Wei, Zhang; Fu-Min, Zhang; Yong-Qiang, Tu*; Xiao-Ping Cao*, Chem–Asian. J, 2011, 6, 2269.
以共同作者发表论文
1. Access to P-Stereogenic Phosphinates via N-Heterocyclic Carbene-Catalyzed Desymmetrization of Bisphenols. Zhijian Huang, Xuan Huang, Baosheng Li, Chengli Mou, Song Yang, Bao-An Song, and Yonggui Robin Chi. J. Am. Chem. Soc, 2016, 138, 7524.
2. N-Heterocyclic Carbene-Catalyzed δ-Carbon LUMO Activation of Unsaturated Aldehydes. Tingshun Zhu, Chengli Mou, Baosheng Li, Marie Smetankova, Bao-An Song, and Yonggui Robin Chi*, J. Am. Chem. Soc, 2015, 137, 5658.
3. Catalytic asymmetric semipinacol rearrangements. Shao-Hua Wang, Bao-Sheng Li and Yong-Qiang Tu, Chem. Commun, 2014, 50, 2393.
4. Construction of fused- and spiro-oxa-[n.2.1] skeletons by a tandem epoxide rearrangement/intramolecular [3+2] cycloaddition of cyclopropanes with carbonyls. Lu-Feng Wang, Zi-Fa Shi, Xiao-Ping Cao*, Bao-Sheng Li and Peng An. Chem. Commun, 2014, 50, 8061.
5. Catalytic intermolecular carbon electrophile induced semipinacol rearrangement. Qing-Wei Zhang, Xiao-Bo Zhang, Bao-Sheng Li, Kai Xiang, Fu-Min Zhang, Shao-Hua Wang and Yong-Qiang Tu*. Chem. Commun, 2013, 49, 1648.
6. Palladium-Catalyzed Cascade Process To Construct 1,2,5-Trisubstituted Pyrroles. Yong-Qiang, Zhang; Dao-Yong, Zhu; Bao-Sheng, Li; Yong-Qiang, Tu*; Yong, Lu; Sho-Hua, Wang. J. Org. Chem, 2012, 77, 4167.
7. Total Synthesis of Malyngamides K, L, and 5′′-epi-C and Absolute Configuration of Malyngamide L. Jun-Tao, Zhang; Xian-Liang, Qi; Jie, Chen; Bao-Sheng, Li; You-Bai, Zhou; Xiao-Ping, Cao*. J. Org. Chem, 2011, 76, 3946.
8. Regiodivergent Annulation of AlkynylIndoles To Construct Spiro-pseudoindoxyl and Tetrahydro-β-carbolines. Yong-Qiang, Zhang; Dao-Yong, Zhu; Zhi-Wei, Jiao; Bao-Sheng, Li; Fu-Min, Zhang; Yong-Qiang, Tu*, Org. Lett, 2011, 13, 3458.
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